上部消化管外科
外来診察 2F/H1 ※初診や再診の受付完了後にお越しください
概要
患者のみなさんへ
上部消化管外科は食物が通過する食道、胃、十二指腸に発生する疾患、また、あらゆる腹部ヘルニア、機能障害(正中弓状靭帯圧迫症候群、逆流性食道炎、高度肥満症、手掌多汗症)を専門的に扱う診療科です。がんに対する手術を中心に診療を行っています。一方、一般施設では対応が難しい高度進行がんや合併症を持つ患者さんの治療にも積極的に取り組んでおり、高度進行食道がんに対する拡大手術や機能温存(声を残す)手術においては、日本におけるオピニオンリーダーとして全国から紹介をいただいております。また、手術を受けた後の生活の事も踏まえ、がんの根治と安全性やQOL維持のバランスを考慮した治療を行っています。その際、患者さんやご家族の気持ちを十分に聞きながら、それぞれの患者さんにとって一番良い治療を目指します。
当科では、以下のような疾患を扱っています。
消化管悪性腫瘍(食道がん、胃がん、GIST、神経内分泌腫瘍など)、下血、吐血、腹痛、腹部腫瘤、ヘルニア、肥満、糖尿病、胃食道逆流症(GERD)、逆流性食道炎、急性腹症
オンライン・セカンドオピニオン外来
特色・強み

胃がんや食道がんに対する内視鏡手術やロボット支援下手術を積極的に導入し、がんの根治と機能温存を低侵襲で両立させた治療を提供しています。また、他施設では対応できない高度進行がんに対する手術も数多く手掛けております。関係各科と協同して化学療法・放射線治療などの集学的治療や新薬の治験も多数行っています。

食道がん・胃がんも他のがんと同様に高齢者が増加し、老々介護や一人暮らし世帯が増えています。がん患者さんがより元気に過ごしていただくために、入院中のみならず外来での継続的な栄養指導やリハビリ、患者会での患者間交流や地域との連携を積極的に行っています。

肥満や糖尿病などの代謝疾患に対する減量・代謝改善手術も実施しており、日本肥満症治療学会の施設認定も受けています。また、糖尿病に対する腹腔鏡下スリーブバイパス術も受けていただくことが可能です。
主な対象疾患
- 消化管悪性腫瘍(食道がん、胃がん、GIST、神経内分泌腫瘍など)
- 食道・胃・十二指腸の良性腫瘍
- 肥満・糖尿病
- 鼠径ヘルニア・腹壁ヘルニア
- 胃食道逆流症(GERD)・逆流性食道炎
- 急性腹症
- アカラシア
各種実績
- 診療実績(2025年度版)
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外来新患者数 431名 外来延患者数 7,970名 入院新患者数 612名 入院延患者数 9,688名 - 手術・検査実績(2025年度版)
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食道 食道がん手術 102例
(ロボット手術38例、胸(腹)腔鏡78例、その他16例)胃・十二指腸 胃がん手術 89例
(ロボット手術10例、腹腔鏡78例、開腹1例)十二指腸腫瘍手術 8例
(腹腔鏡・内視鏡合同手術:D-LECS)GIST 13例 減量・代謝改善手術 7例 急性腹症など 13例 ヘルニア 鼠経ヘルニア 71例
(腹腔鏡44例、前方アプローチ37例) - 論文
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1 Membrane topology inversion of GGCX mediates cytoplasmic carboxylation for antiviral defense. Okazaki T, Nozaki K, Morimoto N, Otobe Y, Saito R, Abe S, Okajima M, Yoshitane H, Hatta T, Iemura SI, Natsume T, Kosako H, Yamasaki M, Inoue S, Kondo T, Koseki H, Gotoh Y.
Science. 2025 Jul 3;389(6755):84-91. doi: 10.1126/science.adk9967. Epub 2025 Jul 3. PMID: 40608933.2 Blood DNA virome associates with autoimmune diseases and COVID-19. Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K; Japan COVID-19 Task Force; Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, Kimura A, Noguchi E, Sano S, Inohara H, Fujimoto M, Inoue Y, Yamaguchi E, Ogawa S, Kanai T, Morita A, Matsuda F, Tamari M, Kumanogoh A, Tanaka Y, Ohmura K, Fukunaga K, Imoto S, Miyano S, Parrish NF, Okada Y.
Nat Genet. 2025 Jan;57(1):65-79. doi: 10.1038/s41588-024-02022-z. Epub 2025 Jan 3. PMID: 39753770; PMCID: PMC11735405.3 Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution. Edahiro R, Sato G, Naito T, Shirai Y, Saiki R, Sonehara K, Tomofuji Y, Yamamoto K, Namba S, Sasa N, Nagao G, Wang QS, Takahashi Y, Hasegawa T, Kishikawa T, Suzuki K, Liu YC, Motooka D, Takuwa A, Tanaka H, Azekawa S; Japan COVID-19 Task Force; Namkoong H, Koike R, Kimura A, Imoto S, Miyano S, Kanai T, Fukunaga K, Uemura M, Morita T, Kato Y, Hirata H, Takeda Y, Doki Y, Eguchi H, Okuzaki D, Sakakibara S, Ogawa S, Kumanogoh A, Okada Y.
Nat Genet. 2025 Aug;57(8):1905-1921. doi: 10.1038/s41588-025-02266-3. Epub 2025 Jul 28. PMID: 40721531; PMCID: PMC12339405.4 Mechanical Thrombectomy Access in Africa: ; Global Executive Committee of the MT-GLASS Study. Alejo G, Prasad S, Otite FO, Jones EM, Yavagal DR, Ortega-Gutierrez S, Lamou EGB, Desai SM, Asif KS, Gebreyohanns M; Global Executive Committee of the MT-GLASS Study.
Mechanical Thrombectomy Access in Africa:5 Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy: A Randomized Clinical Trial With Open-Label Extension. Adams D, Wixner J, Polydefkis M, Berk JL, Conceição IM, Dispenzieri A, Peltier A, Ueda M, Bender S, Capocelli K, Jay PY, Yureneva E, Obici L; patisiran
Global OLE study group.
JAMA Neurol. 2025 Mar 1;82(3):228-236. doi: 10.1001/jamaneurol.2024.4631. PMID: 39804640; PMCID: PMC11894486.6 Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases. Bhak Y, Raptis V, He Y, Nakanishi T, Macdonald-Dunlop E, Sagiya Y, Morisaki T, Matsuda K; BioBank Japan Project; Japan COVID-19 Task Force; Kanai A, Suzuki Y, Oda Y, Kamatani Y, Namkoong H, Saiki R, Kimura A, Koike R, Ogawa S, Miyano S, Imoto S, Kanai T, Fukunaga K, Okada Y, Mälarstig A, Tenesa A.
Sci Rep. 2025 Aug 28;15(1):31721. doi: 10.1038/s41598-025-10031-z. PMID: 40877285; PMCID: PMC12394655.7 Semaglutide and Hospitalizations in Patients With Obesity and Established Cardiovascular Disease: An Exploratory Analysis of the SELECT Randomized Clinical Trial. Nicholls SJ, Ryan DH, Deanfield J, Ferreira D, Lang CC, Lincoff AM, Lingvay I, Lübker C, Terns PP, Rasmussen S, Stensen S, Weeke PE, Kahn SE; SELECT Trial Investigators.
JAMA Cardiol. 2026 Feb 1;11(2):156-164. doi: 10.1001/jamacardio.2025.4824. Erratum in: JAMA Cardiol. 2026 May 6.
doi:10.1001/jamacardio.2026.1518. PMID: 41433034; PMCID:PMC12728728.8 Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database. Gajdos L, Buetti N, Tabah A, Ruckly S, Akova M, Sjöval F, Arvaniti K, de Waele J, Bracht H, Barbier F, Timsit JF; EUROBACT-2 Study Group, the European Society of Intensive Care Medicine (ESICM), the European Society of Clinical Microbiology, the Infectious Diseases (ESCMID) Study Group for Infections in Critically Ill Patients (ESGCIP) and the OUTCOMEREA Network.
Intensive Care Med. 2025 Oct;51(10):1968-1970. doi: 10.1007/s00134-025-08071-0. Erratum for: Intensive Care Med. 2025 Mar;51(3):518-528. doi: 10.1007/s00134-025-07857-6. PMID: 40828470..9 Correction: Shortening antibiotic therapy duration for hospital-acquired bloodstream
infections in critically ill patients: a causal inference model from the
international EUROBACT-2 database.Gajdos L, Buetti N, Tabah A, Ruckly S, Akova M, Sjöval F, Arvaniti K, de
Waele J, Bracht H, Barbier F, Timsit JF; EUROBACT-2 Study Group, the European
Society of Intensive Care Medicine (ESICM), the European Society of Clinical
Microbiology, the Infectious Diseases (ESCMID) Study Group for Infections in
Critically Ill Patients (ESGCIP) and the OUTCOMEREA Network.
Intensive Care Med. 2025
Oct;51(10):1968-1970. doi: 10.1007/s00134-025-08071-0. Erratum for: Intensive
Care Med. 2025 Mar;51(3):518-528. doi: 10.1007/s00134-025-07857-6. PMID:
40828470.10 Efficacy and safety of taxane plus ramucirumab for advanced gastric cancer after chemotherapy plus nivolumab. Matsumoto T, Ikoma T, Makiyama C, Yasuda T, Boku S, Nakasya A, Shibata N, Nagai H, Tsuduki T, Matsumoto Y, Yasui H, Higashi R, Sasamoto A, Satake H, Inoue K, Kanai M, Yamasaki M.
Sci Rep. 2025 Aug 7;15(1):28841. doi: 10.1038/s41598-025-13714-9. PMID: 40770215; PMCID: PMC12328655.11 A retrospective cohort study on short-term outcomes after oesophagectomy for cancer in Japan. Makino T, Endo H, Yamamoto H, Hasegawa H, Yamasaki M, Yasuda T, Ueno H, Shirabe K, Kimura Y, Takeuchi H, Eguchi H, Doki Y.
Br J Surg. 2025 Nov 29;112(12):znaf276.
doi: 10.1093/bjs/znaf276. PMID: 41400037.12 Advanced fixation techniques for high-sensitivity molecular imaging: effectiveness of glyoxal fixation for immunostaining. Konno K, Yamasaki M, Watanabe M.
Anat Sci Int. 2025 Sep;100(4):562-567. doi: 10.1007/s12565-025-00848-z. Epub 2025 May 26. PMID: 40418501.13 Vaccine-related environments and patient preferences in Japanese patients with autoimmune rheumatic diseases. Oku K, Yamada H, Ikenoue T, Akizuki M, Hagiyama H, Ideguchi H, Ihata A, Kakutani T, Kawahata K, Matsui T, Obata J, Ohno S, Sato S, Sawa N, Suda A, Taguchi H, Takeno M, Ueda A, Yamasaki M, Yamaoka K.
Mod Rheumatol. 2025 Oct 28;35(6):997-1008. doi:10.1093/mr/roaf061. PMID: 40626929.14 The transcription factor ZFP64 promotes activity-dependent synapse elimination during postnatal cerebellar development. Zhang J, Watanabe T, Miyazaki T, Yamasaki M, Konno K, Okuno Y, Matsuyama K, Noro T, Watanabe M, Uesaka N, Kano M.
iScience. 2025 May 26;28(6):112746. doi: 10.1016/j.isci.2025.112746. PMID: 40546958; PMCID: PMC12178792.15 GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand. Suzuki T, Kadoya K, Endo T, Yamasaki M, Watanabe M, Iwasaki N.
Adv Sci (Weinh). 2025 Jan;12(4):e2400812. doi: 10.1002/advs.202400812. Epub 2024 Dec 4. PMID: 39630029; PMCID: PMC11775530.16 Prognostic Value of Intrarenal Venous Flow Analysis Using Pulsed-Wave Doppler. Morita T, Terukina H, Yamasaki M.
J Vet Intern Med. 2025 Nov-Dec;39(6):e70260. doi: 10.1111/jvim.70260. Erratum in: J Vet Intern Med. 2025 Nov-Dec;39(6):e70266. doi: 10.1111/jvim.70266. PMID:41041687; PMCID: PMC12491933.17 Evaluating the discrepancies between evidence-based and community standard practices in the endoscopic examination of Barrett's esophagus: a nationwide survey in Japan. Iwaya Y, Iijima K, Hikichi T, Amano Y, Endo M, Goda K, Suga T, Yamasaki M, Kawamura M, Sasaki F, Tanaka K, Namikawa K, Muto M, Takeuchi H, Ishihara R.
Esophagus. 2025 Jul;22(3):349-359. doi: 10.1007/s10388-025-01127-6. Epub 2025 Apr 19. PMID: 40252108; PMCID: PMC12167344.18 Preferential Localization of STIM1 to Dendritic Subsurface ER Structures in Mouse Purkinje Cells. Nomura S, Yamasaki M, Miyazaki T, Konno K, Watanabe M.
J Neurosci. 2025 Apr 16;45(16):e1829242025. doi: 10.1523/JNEUROSCI.1829-24.2025. PMID: 40086872; PMCID:PMC12005364.19 Cumulative pretrigger progesterone levels are not superior to single-day levels for predicting a failed cycle in fresh embryo transfer cycles. Yamasaki M, Flannagan K, Boedeker D, Dolitsky S, Banks N, Decherney A, Hariton E, Harris BS, Imudia A, Kallen C, Kanter J, Levy M, Romanski P, Uhler M, Devine K, Hill M.
Fertil Steril. 2025 Oct;124(4):772-774. doi: 10.1016/j.fertnstert.2025.04.024. Epub 2025 Apr 23. PMID: 40280225.20 The role of FLVCR1 and FLVCR2 in choline transport in the Caco-2 intestinal epithelial cell model and rat small intestine. Yasujima T, Namba C, Azuma Y, Shinoda Y, Matake I, Yamasaki M, Morimoto H, Namai M, Kusuhara H, Inoue K, Yamashiro T, Yuasa H.
Biochim Biophys Acta Mol Basis Dis. 2025 Aug;1871(6):167883. doi: 10.1016/j.bbadis.2025.167883. Epub 2025 May 2. PMID: 40320184.21 CS-Lung-003 Investigator. Promising Effectiveness of Combined Chemotherapy and Immunotherapy in Patients with Advanced Non-small Cell Lung Cancer: A Real-World Prospective Observational Study (CS-Lung-003). Kanaji N, Nishii K, Tsubata Y, Nakao M, Okuno T, Okawa S, Takata K, Kodani M, Yamasaki M, Fujitaka K, Kubota T, Inoue M, Watanabe N, Hotta K.
Acta Med Okayama. 2025 Jun;79(3):167-176. doi: 10.18926/AMO/68724. PMID: 40574255.22 Pre-Operative Resistance Training and Amino Acid Supplementation in Frail Patients With Gastrointestinal Cancer: A Randomized Clinical Trial. Fujimoto T, Akasaka H, Yasunobe Y, Yoshida S, Onishi Y, Minami T, Terashima K, Shirai M, Isaka M, Tanaka M, Sugimoto K, Koriyama H, Takami Y, Yamasaki M, Yamashita K, Noda T, Takahashi H, Eguchi H, Doki Y, Rakugi H, Yamamoto K.
Geriatr Gerontol Int. 2025 Dec;25(12):1765-1773. doi: 10.1111/ggi.70226. Epub 2025 Oct 18. PMID: 41108598; PMCID: PMC12719127.23 Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy. Motoori M, Tanaka K, Miyata H, Yamasaki M, Shiraishi O, Takeno A, Makino T, Sugimura K, Yasuda T, Doki Y.
Ann Gastroenterol Surg. 2025 Jan 20;9(4):678-686. doi: 10.1002/ags3.12914. PMID: 40607301; PMCID: PMC12211104.24 Benefits of neoadjuvant chemotherapy: is the prognosis of ypN0 patients after neoadjuvant chemotherapy comparable to that of pN0 patients undergoing surgery alone? Shiraishi O, Tanaka K, Makino T, Sugase T, Kanemura T, Takeno A, Sugimura K, Motoori M, Kimura Y, Hirao M, Fujitani K, Miyata H, Yano M, Yamasaki M, Doki Y, Yasuda T.
Esophagus. 2025 Jul;22(3):373-381. doi: 10.1007/s10388-025-01132-9. Epub 2025 May 20. PMID: 40394433; PMCID: PMC12167258.25 Nanovesicles derived from edible plants: a new player that contributes to the function of foods. Yamasaki M, Yamasaki Y, Oshima T.
Biosci Biotechnol Biochem. 2025 Jan 24;89(2):179-186. doi: 10.1093/bbb/zbae198. PMID: 39730148.26 A Chest Wall Myofibroma in an Adult. Kubouchi Y, Haruki T, Wada T, Yamasaki M, Yasuda K, Fujiwara W, Makishima K, Miyamoto T, Matsui S, Umekita Y, Hisaoka M, Tanaka Y.
Surg Case Rep. 2025;11(1):24-0156. doi: 10.70352/scrj.cr.24-0156. Epub 2025 Apr 2. PMID: 40230826; PMCID: PMC11994292.27 Revisiting Cancer Cachexia Staging: Introducing an "At Risk" Category Based on AWGC Components. Sakaguchi T, Maeda K, Yamasaki M, Mori N.
Thorac Cancer. 2025 Nov;16(22):e70188. doi: 10.1111/1759-7714.70188. PMID: 41261784; PMCID:PMC12630547.28 Molecular and Anatomical Strengthening of "Winner" Climbing Fiber Synapses in Developing Mouse Purkinje Cells. Nitta A, Yamasaki M, Miyazaki T, Konno K, Yoshimura H, Watanabe M.
J Neurosci. 2025 Apr 9;45(15):e2156242025. doi: 10.1523/JNEUROSCI.2156-24.2025. PMID: 40015986; PMCID: PMC11984076.29 Magnetic Resonance Cholangiopancreatography for Cholangiopancreatic Duct Imaging in Dogs. Fujiwara R, Yamamoto K, Yamasaki M, Ohno K.
Vet Radiol Ultrasound. 2025 Jan;66(1):e70008. doi: 10.1111/vru.70008. PMID: 39826111; PMCID: PMC11742707.30 Mpox virus OPG175 negatively regulates viral replication by controlling Wnt signaling. Nakata Y, Yamasaki M, Watanabe Y, Uriu K, Hashimoto R, Yamamoto T; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sato K, Saito A, Takayama K.
iScience. 2025 Nov 19;28(12):114105. doi: 10.1016/j.isci.2025.114105. PMID: 41488350; PMCID: PMC12756559.31 A Case of Ischemic Pancreatitis After Acute Aortic Dissection. Fujieda M, Santanda T, Sato A, Hara R, Nakamura Y, Shibata S, Yamasaki M.
Cureus. 2025 Feb 16;17(2):e79075. doi: 10.7759/cureus.79075. PMID: 40104487; PMCID: PMC11915062.32 ASO Author Reflections: Rethinking Surgical Intervention in Esophageal Cancer with Para-Aortic Lymph Node Metastasis. Tanaka K, Sugimura K, Matsuura N, Shiraishi O, Momose K, Yamashita K, Sugase T, Kanemura T, Makino T, Takeno A, Kawabata R, Motoori M, Kimura Y, Yamasaki M, Miyata H, Fujitani K, Yasuda T, Yano M, Eguchi H, Doki Y.
Ann Surg Oncol. 2025 Dec;32(13):10158-10159. doi: 10.1245/s10434-025-18227-3. Epub 2025 Oct 8. PMID: 41060603.33 Three-Year Outcomes of a Multicenter Study of Japanese-Style Laparoscopic Sacrocolpopexy. Kuwata T, Kashihara H, Kato C, Takeyama M, Yamaguchi A, Moriyama Y, Nakai C, Miwa K, Araki H, Narushima M, Yamasaki M, Hirama H, Okazoe H.
Int Urogynecol J. 2025 Jan;36(1):71-78. doi: 10.1007/s00192-024-05954-6. Epub 2024 Oct 29. PMID: 39470780.34 [Investigation of the Usefulness of Intermittent Self-Dilation after Transurethral Surgery for Urethral Stricture] Yokoi T, Someya R, Tanaka E, Yamasaki M, Iijima H, Takahashi T, Ueda M,
Shiraishi Y, Yoshimura K.
Hinyokika Kiyo. 2025 Apr;71(4):105-109. Japanese. doi: 10.14989/ActaUrolJap_71_4_105. PMID:
40350691.35 Distinct roles of two thalamostriatal systems in visually triggered decision-making in common marmosets. Kato S, Sugawara M, Yamasaki M, Watanabe M, Inoue KI, Nakamura K, Koketsu D, Chiken S, Nambu A, Takada M, Kobayashi K.
iScience. 2025 Jun 17;28(7):112921. doi: 10.1016/j.isci.2025.112921. PMID: 40678542;
PMCID: PMC12270013.36 Efficient Drug Release from Liposomes Introduced Tetrazine Derivatives with Pyrimidine Rings Using Click Chemistry. Yamasaki M, Munekane M, Kannaka K, Sano K, Yamasaki T, Mukai T.
Chem Pharm Bull (Tokyo). 2025;73(2):108-111. doi: 10.1248/cpb.c24-00591. PMID: 39993767.37 Interfacility Transfer and Early Mortality in Type A Acute Aortic Dissection: A Multicenter Registry Study. Takahashi T, Yoshino H, Shimokawa T, Usui M, Kunihara T, Akutsu K, Ogino H, Kawata M, Yamasaki M, Fujii T, Takagi T, Imazuru T, Kojima K, Yamamoto T, Kohsaka S, Takayama M.
JACC Asia. 2025 Nov;5(11):1520-1523. doi: 10.1016/j.jacasi.2025.08.021. PMID: 41198379; PMCID: PMC12673821.38 Fatty amines and 1-monoglycerides with cytotoxic activity serve as ligands for a multipurpose receptor CD36. Tsuzuki S, Yamasaki M, Sugawara T, Manabe Y, Toyoda M, Mizutani K, Sasaki T.
Biomed Res. 2025;46(5):189-202. doi: 10.2220/biomedres.46.189. PMID: 41016773.39 Unique Complex Structure and Mechanism of Physisorption of Defect-Free Cyclic Poly(ethylene glycol) onto Gold Nanoparticles. Watanabe T, Yamasaki M, Nakai T, Pottammal BA, Maruyama Y, Iwase H, Ryoki A, Gao T, Li F, Isono T, Tajima K, Satoh T, Sato SI, Yamamoto T.
Langmuir. 2025 Jun 10;41(22):13993-14007. doi: 10.1021/acs.langmuir.5c00930. Epub 2025 May 26. PMID: 40420393.40 Influence of CYP1A and AhR modulation on polycyclic aromatic hydrocarbon-induced developmental defects in Japanese medaka. Fukugami S, Yamasaki M, Kokushi E, Uno S.
Aquat Toxicol. 2025 Mar;280:107267. doi: 10.1016/j.aquatox.2025.107267. Epub 2025 Feb 5. PMID: 39933340.41 Intravenous administration of [90]Y-labeled polyoxazoline combined with tumor heating potently inhibits tumor growth in mice. Sano K, Mizukami T, Tanaka T, Nagayama T, Nakata M, Yamasaki M, Fukada T, Haratake Y, Munekane M, Yamasaki T, Mukai T.
Int J Pharm. 2025 Jan 25;669:125103. doi: 10.1016/j.ijpharm.2024.125103. Epub 2024 Dec 19. PMID: 39708850.42 Analysis of gene expression of Babesia gibsoni cultured with diminazene aceturate using RNA sequencing. Matsuda N, Ito M, Nukada Y, Toyoma M, Nagai K, Motegi T, Morita T, Yamasaki M.
J Vet Med Sci. 2025 Feb 4;87(2):181-188. doi: 10.1292/jvms.24-0395. Epub 2024 Dec 30. PMID: 39756884; PMCID: PMC11830443.43 MKDESIGNER and TASEQ: a set of tools for plant genotyping by targeted amplicon sequencing. Chigira K, Yamasaki M, Ookawa T.
BMC Bioinformatics. 2025 Jul 11;26(1):175. doi: 10.1186/s12859-025-06211-3. PMID: 40646497; PMCID: PMC12247248.44 Comparing gestational carrier with uterine transplantation in uterine-factor infertility: a cost-effectiveness analysis. Combs JC, Yamasaki MU, Dougherty M, Hunkler K, Osmundsen EB, Roura-Monllor J, Stillman RJ, Hill MJ, Devine K, DeCherney AH, Nelson RE, O'Brien JE.
Fertil Steril. 2025 Jul;124(1):134-143. doi: 10.1016/j.fertnstert.2025.01.012. Epub 2025 Jan 22.
Erratum in: Fertil Steril. 2025 Oct;124(4):797-798. doi: 10.1016/j.fertnstert.2025.07.1203. PMID: 39848421; PMCID: PMC12170173.45 Association of the single nucleotide polymorphism rs1697421 with an increased postprandial serum phosphorus level. Nii-Nakayama S, Katsumoto M, Ishitani S, Narasaki Y, Seko C, Yamasaki M, Ohminami H, Ohnishi K, Masuda M, Yamanaka-Okumura H, Yamamoto H, Taketani Y.
Clin Exp Nephrol. 2025 Aug;29(8):1021-1031. doi: 10.1007/s10157-025-02644-5. Epub 2025 Feb 28. PMID: 40019722.46 Arterial Thromboembolism in Patients With Advanced Lung Cancer: Secondary Analyses of the Rising-VTE/NEJ037 Study. Furuya N, Tsubata Y, Hotta T, Yokoyama T, Yamasaki M, Ishikawa N, Fujitaka K, Kubota T, Kobayashi K, Isobe T.
Cancer Med. 2025 Jan;14(1):e70568. doi: 10.1002/cam4.70568. PMID: 39783855; PMCID: PMC11714229.47 Acute Hemorrhagic Leukoencephalitis with Concurrent Retinal Vasculitis in an Elderly Japanese Patient. Yamaguchi Y, Sawaya R, Shichinohe N, Tanei ZI, Yamasaki M, Tomeoka F, Ajiki M, Takada T, Shinohara T, Asaoka K.
Intern Med. 2025 Jan 15;64(2):301-306. doi: 10.2169/internalmedicine.3518-24. Epub 2024 Jun 20. PMID: 38897959; PMCID: PMC11802224.48 [Delayed onset of diplopia and visual impairment after herpes zoster ophthalmicus]. Hattori Y, Taniguchi A, Inoue R, Inoue N, Kobayashi K, Yamasaki M.
Rinsho Shinkeigaku. 2025 Dec 19;65(12):909-911. Japanese. doi: 10.5692/clinicalneurol.cn-002146. Epub 2025 Nov 15. PMID: 41242736.49 Antennal Responses to Volatiles Related to Host Location in the Ambrosia Beetle Platypus quercivorus (Murayama). Okada R, Ito Y, Yamasaki M.
J Chem Ecol. 2025 Feb 25;51(2):27. doi: 10.1007/s10886-025-01580-8. PMID: 39994068.50 Marked enhancement of synergistic antioxidative activity of astaxanthin and curcumin by co-encapsulation in a liposomal formulation. Yamasaki M, Yoneda S, Maoka T, Kogure K.
J Clin Biochem Nutr. 2025 Nov 1;77(3):209-215. doi: 10.3164/jcbn.25-53. Epub 2025 Aug 8. PMID: 41312009; PMCID: PMC12646837.51 In Vitro and In Vivo Characterization of 40 kDa PEGylated Adrenomedullin in a DSS-Induced Colitis Model. Kitamura K, Akashi E, Nagata S, Kita T, Yamasaki M.
Int J Mol Sci. 2025 Sep 25;26(19):9373. doi: 10.3390/ijms26199373. PMID: 41096644; PMCID: PMC12524408.52 Differences of benzo[a]anthracene-and pyrene-induced disruption of craniofacial chondrogenesis in Japanese medaka. Fukugami S, Yamasaki M, Kokushi E, Uno S.
Aquat Toxicol. 2026 Feb;291:107696. doi: 10.1016/j.aquatox.2025.107696. Epub 2025 Dec 26. PMID: 41478200.53 Drastic mycorrhizal community shifts in Sceptridium ferns during the generation transition from fully mycoheterotrophic gametophytes to photosynthetic sporophytes. Suetsugu K, Okada H, Hirota SK, Yamasaki M, Imaichi R, Ebihara A.
New Phytol. 2025 Feb;245(4):1705-1717. doi: 10.1111/nph.20330. Epub 2024 Dec 7. PMID: 39645585; PMCID:PMC11754932.54 Pulmonary Smooth Muscle Hyperplasia Difficult to Differentiate from Primary Lung Cancer: A Case Report. Yamasaki M, Kubouchi Y, Wada T, Fujiwara W, Matsui S, Tanaka Y.
Surg Case Rep. 2025;11(1):25-0428. doi: 10.70352/scrj.cr.25-0428. Epub 2025 Aug 28. PMID: 40909326; PMCID: PMC12405001.55 Reliability and Validity of the Japanese Version of the eHealth Literacy Scale in Community-Dwelling Older Adults: A Cross-Sectional Study. Tsujimoto T, Abe T, Kuroda Y, Yamasaki M, Isomura M.
Eur J Investig Health Psychol Educ. 2025 Dec 19;16(1):1. doi: 10.3390/ejihpe16010001. PMID: 41590011; PMCID: PMC12839868.56 Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised 1-[13]C pyruvate MRI. Tomiyama H, Yamasaki M, Isagawa T, Takeda N, Hashimoto T, Hirata H, Matsumoto S.
Discov Nano. 2025 Aug 6;20(1):128. doi: 10.1186/s11671-025-04304-9. PMID: 40767899; PMCID: PMC12328871.57 Genomic analysis highlights the conservation significance of Torenia concolor (Linderniaceae) from the periphery of its distribution range. Isagi Y, Shimizu T, Kobayashi Y, Suyama Y, Tokuhiro C, Kokubugata G, Ito T, Chung KF, Abe A, Makino T, Yamasaki M.
J Plant Res. 2025 Nov;138(6):959-969. doi: 10.1007/s10265-025-01659-z. Epub 2025 Aug 19. PMID: 40828360; PMCID: PMC12638373.58 Detection of early renal perfusion changes by contrast-enhanced ultrasonography in dogs with preclinical myxomatous mitral valve disease. Kamata S, Morita T, Yamasaki M.
Vet Radiol Ultrasound. 2025 Jan;66(1):e13459. doi: 10.1111/vru.13459. Epub 2024 Nov 12. PMID: 39531152; PMCID: PMC11617612.59 MRI outperforms CT for tracheal and vascular invasion staging in esophageal cancer. Kono Y, Harino T, Yamamoto S, Ogasawara R, Akita K, Yamasaki M, Tanigawa N.
Eur Radiol. 2026 Apr;36(4):2842-2850. doi: 10.1007/s00330-025-12080-4. Epub 2025 Oct 25. PMID: 41137917; PMCID: PMC13035738.60 An Unusual Case of a Central Pontine Myelinolysis Associated with Primary Splenic Diffuse
Large B-cell Lymphoma.Yamasaki M, Taniguchi A, Minami H, Tada T, Yabana T, Naito Y.
Intern Med. 2025 May 15;64(10):1574-1580. doi: 10.2169/internalmedicine.3926-24. Epub 2024 Oct 4. PMID: 39370257;PMCID: PMC12183411.61 Surgical and long-term outcomes of combined organ resection for esophageal cancer invading adjacent organs: Experience of 90 consecutive cases. Makino T, Yamasaki M, Nakai S, Momose K, Yamashita K, Tanaka K, Shimamura K, Motoori M, Kurokawa Y, Kimura Y, Nakajima K, Miyagawa S, Eguchi H, Doki Y.
J Thorac Cardiovasc Surg. 2025 Oct;170(4):957-968. doi: 10.1016/j.jtcvs.2025.01.017. Epub
2025 Jan 24. PMID: 39864736.62 Long-Term Survival of Two Versus Three Courses of Preoperative Cisplatin and Fluorouracil Plus Docetaxel for Locally Advanced Esophageal Cancer: A Multicenter Randomized Phase II Trial. Sugase T, Miyata H, Kanemura T, Matsuura N, Makino T, Yamasaki M, Tanaka K, Yamashita K, Momose K, Shiraishi O, Sugimura K, Motoori M, Fujitani K, Takeno A, Hirao M, Kimura Y, Satoh T, Yano M, Doki Y, Yasuda T.
Ann Gastroenterol Surg.2025 May 10;9(6):1144-1154. doi: 10.1002/ags3.70036. PMID: 41199984; PMCID: PMC12586935.63 Lactiplantibacillus plantarum
Strain 06CC2 Attenuates Fat Accumulation and Modulates the Gut Microbiota in a Mouse Model of Early-Stage Diet-Induced Obesity.Matsusaki T, Takakura C, Ichitani K, Tsend-Ayush C, Kataoka H, Fukushima T, Kurogi J, Nishiyama K, Ogawa K, Shinyama T, Nakano T, Yamasaki M.
Nutrients.2025 Dec 10;17(24):3855. doi: 10.3390/nu17243855. PMID:41470800;PMCID: PMC12736013.64 QTN detection and candidate gene identification for improved eating and cooking quality in rice using GWAS and PLS regression analysis. Hori K, Shenton M, Mochizuki K, Suzuki K, Iijima K, Kuya N, Shu K, Ono K, Kinoshita Y, Sugimoto K, Umemoto T, Yonemaru JI, Yamasaki M, Takeuchi Y, Ebana K, Tsujii Y.
Theor Appl Genet. 2025 Feb 26;138(3):58. doi: 10.1007/s00122-025-04850-x. PMID: 40009082;
PMCID: PMC11865119.65 Association between the COVID-19 pandemic and short-term outcomes after esophagectomy for esophageal cancer in facilities with and without board-certified esophageal surgeons: a nationwide retrospective cohort study. Takeuchi M, Endo H, Hibi T, Seishima R, Takemura Y, Yamamoto H, Maeda H, Taketomi A, Kakeji Y, Seto Y, Ueno H, Watanabe M, Daiko H, Yasuda T, Yamasaki M, Mori M, Takeuchi H, Shirabe K, Kitagawa Y.
Esophagus. 2025 Jan;22(1):37-46. doi: 10.1007/s10388-024-01094-4. Epub 2024 Dec 2. PMID: 39621200.66 Outcome of Conversion Surgery After Induction Therapy for Esophageal Cancer with Synchronous Para-Aortic Lymph Node Metastasis: A Multi-institutional Retrospective Study. Tanaka K, Sugimura K, Matsuura N, Shiraishi O, Momose K, Yamashita K, Sugase T, Kanemura T, Makino T, Takeno A, Kawabata R, Motoori M, Kimura Y, Yamasaki M, Miyata H, Fujitani K, Yasuda T, Yano M, Eguchi H, Doki Y.
Ann Surg Oncol.2025 Nov;32(12):9270-9280. doi: 10.1245/s10434-025-18042-w. Epub 2025 Aug 20. PMID: 40833540; PMCID: PMC12534259.67 Proton beam-based chemoradiotherapy versus surgery plus adjuvant chemotherapy for esophageal squamous cell carcinoma: a comparison of the long-term survival from a single-center cohort study. Toshiyama S, Honda M, Murakami M, Kikuchi Y, Seto I, Suzuki M, Kawamura H, Takagawa Y, Yamaguchi H, Kato T, Miyakawa T, Takano Y, Hori S, Yamasaki M, Kono K.
Dis Esophagus.025 Nov 1;38(6):doaf099. doi: 10.1093/dote/doaf099. PMID: 41231219.68 Perforated primary adenocarcinoma of the colon with choriocarcinoma differentiation treated with targeted colorectal cancer chemotherapy: a case report. Ishimaru N, Tagami T, Yamasaki M, Niwa K.
AME Case Rep.2025 May 6;9:73. doi: 10.21037/acr-24-252. PMID: 40761192; PMCID: PMC12319603.69 Enhancing vehicle-mountable multiple object tracking systems with embeddable Ising machines. Tatsumura K, Hamakawa Y, Yamasaki M, Oya K, Fujimoto H.
Nat Commun.2025 Dec 17;17(1):584. doi: 10.1038/s41467-025-67282-7. PMID: 41407692; PMCID: PMC12808164.70 Worm-like gold nanocrystals fabricated using a self-assembling peptide and inducing cell death upon exposure to near infrared light. Ahn SA, Ishida K, Watanabe R, Imai T, Yamasaki M, Tomizaki KY.
Bioorg Med Chem Lett.2026 Feb 1;131:130472. doi: 10.1016/j.bmcl.2025.130472. Epub 2025 Nov 11. PMID: 41232784.71 Preoperative assessment of pleural adhesions using computed tomography scan and positron emission tomography in patients with lung cancer. Yasuda K, Yamasaki M, Wada T, Fujiwara W, Miyamoto T, Matsui S, Kubouchi Y, Tanaka Y.
Gen Thorac Cardiovasc Surg.2026 Jan;74(1):73-79. doi: 10.1007/s11748-025-02169-4. Epub 2025 Jun 9. PMID: 40488930.72 Interfacility Transfer and Mortality in Patients With Type A Acute Aortic Dissection - Analysis of the Tokyo Acute Aortic Super- Network Database. Usui M, Yoshino H, Akutsu K, Kunihara T, Shimokawa T, Ogino H, Takahashi T, Watanabe K, Yamasaki M, Imazuru T, Watanabe Y, Kawata M, Fujii T, Yamamoto T, Kohsaka S, Takayama M.
Circ Rep. 2025 Dec 26;8(2):193-200. doi: 10.1253/circrep.CR-25-0207. PMID: 41669512; PMCID: PMC12885549.73 Effectiveness and safety of combination immunotherapy with or without ipilimumab according to PD-L1 expression in patients with non-small cell lung cancer: a multi-center retrospective cohort study. Nomura A, Masuda T, Shimoji K, Takao S, Izumi Y, Araki Y, Takayama Y, Masuda K, Yamaguchi K, Sakamoto S, Horimasu Y, Nakashima T, Iwamoto H, Senoo T, Shoda H, Ishikawa N, Yamasaki M, Hamada H, Okada M, Hattori N.
Transl Lung Cancer Res. 2026 Mar 23;15(3):59. doi: 10.21037/tlcr-2025-aw-1281. Epub 2026 Feb 26. PMID: 41982699; PMCID: PMC13071631.74 Incidence and clinical features of venous thromboembolism in patients with lung cancer in Japan:
results from the CS-Lung-003 prospective observational registry study.Tsubata Y, Kanaji N, Nakao M, Masuda T, Yamasaki M, Kodani M, Ishikawa N, Kozuki T, Inoue M, Nishii K, Hotta K, Kiura K, Isobe T.
Respir Investig. 2026 Jan;64(1):101332. doi: 10.1016/j.resinv.2025.11.011. Epub 2025 Nov 22. PMID: 41275531.
学会認定施設
日本食道学会 食道外科専門医認定施設
日本胃癌学会認定施設A
日本肥満症治療学会 肥満症外科手術(原料・代謝改善手術)認定施設