診療科

下部消化管外科

概要

患者のみなさんへ

下部消化管外科は食物が通過する小腸、大腸に発生する疾患を扱う診療科です。大腸がん（結腸がん、直腸がん）に対する手術を中心に診療を行っています。
多くの内視鏡外科学会技術認定医を擁し、通常のがん手術は全て低侵襲なロボット手術、腹腔鏡手術で行っています。また、一般施設では対応が難しい高度進行がんや合併症を持つ患者さんの治療にも取り組んでおり、がんの根治と安全性やQOL維持のバランスを十分に検討した上で治療方針を決めています。その際、患者さんのお考えを十分に聞き、個々の患者さんにとって一番良い治療を目指します。

次のような疾患を扱っています。
消化管悪性腫瘍（⼤腸がん（結腸がん、直腸がん）、⼩腸がん、GIST、神経内分泌腫瘍など）、炎症性腸疾患（潰瘍性⼤腸炎、クローン病）、肛⾨疾患（内痔核、痔瘻などの⼿術）、後腹膜腫瘍、直腸良性疾患（直腸脱、直腸膣瘻など）、腹壁瘢痕ヘルニア、腸閉塞、急性腹症など

下部消化管外科学講座のHPはこちら

下部消化管外科で手術を受けられる際の手術前後の診療体制について

オンライン・セカンドオピニオン外来

詳細はこちら

特色・強み

・年間約500件の手術（大腸がんの原発切除は約300件）を行っています。
・腹腔鏡手術、ロボット手術を積極的に取り入れ、体に優しい手術を行っています。
（内視鏡外科学会技術認定医のもと、大腸がん手術の約99％に腹腔鏡手術、ロボット手術を施行しています）
・直腸がんに対して、可能な限り肛門を温存します。
（下部直腸がんに対し、90%の症例で肛門温存手術を行っています）
また、根治性を担保し、術後の機能（排尿・性機能）を最大限に温存しています。
・結腸がん・直腸がんに対して、ロボット手術を行っています。
（内視鏡外科学会ロボット手術プロクターのもとロボット手術を施行しています）
・進行下部直腸がんに対して、腹腔鏡、ロボット手術で側方リンパ節郭清を行っています。
・閉塞性大腸がんや局所進行直腸がんに対して、集学的治療を行っています。

・局所進行直腸がんに対しては、①原発腫瘍の縮小（局所再発の予防）、②ダウンステージ、③微小転移の制御（遠隔再発率の低下）などを目的として、術前放射線化学療法、術前化学療法を行い、手術へと繋げていきます。直腸がんに対して術前治療を施行することによって、直腸がんが消失することもあります。
また近年、術前に放射線治療と全身化学療法を施行するTotal Neoadjuvant Therapy（TNT）という治療法の開発が進んでいます。当科でも積極的にTNTの治療開発を行っており、直腸がんが消失する割合は約30－40％まで上昇しています。その場合は、患者さんと十分に話し合った上で、手術を施行せずに経過観察を行うという選択肢も存在します。
手術を施行しない場合、人工肛門の心配や排便機能障害が生じることがないため、非常に良好な生活の質を維持することが可能であると考えています。

大腸癌の腹膜播種や腹膜偽粘液腫は、従来、治療が難しい病態と考えられてきました。しかし現在では、病変の広がりや全身状態を詳細に評価し、腫瘍を切除できると判断された患者さんでは、手術によって根治や長期生存が期待できる場合があります。
当科では、「腹膜播種がある」という理由だけで治療の可能性を閉ざすことなく、画像検査や腹腔内所見、他臓器への転移、患者さんの全身状態などを総合的に評価し、手術による完全切除の可能性を最大限検討します。切除可能と判断した場合には、根治または長期生存を目指し、腹膜病変に加えて、必要に応じて病変が及ぶ腸管、大網、骨盤内臓器などを含めた外科治療を行います。また、手術だけでなく、薬物療法や放射線治療を適切に組み合わせ、関連診療科と連携しながら、患者さん一人ひとりの病状や治療目標に応じた集学的治療を提供します。これまで「手術は難しい」と説明された患者さんについても、治療の可能性を改めて検討します。

主な対象疾患

消化管悪性腫瘍（大腸がん（結腸がん、直腸がん）、小腸がん、GIST、神経内分泌腫瘍など）
炎症性腸疾患（潰瘍性大腸炎、クローン病）
肛門疾患（内痔核、痔瘻などの手術）
後腹膜腫瘍
直腸良性疾患（直腸脱、直腸膣瘻など）
腸閉塞
急性腹症
腹壁瘢痕ヘルニア

各種実績

診療実績（2025年度版）: 外来新患者数 371名

外来延患者数 9,281名

入院新患者数 810名

入院延患者数 10,420名
手術・検査実績（2025年度版）: 大腸

総手術数 537例

初発大腸がん 283例
（開腹術 3例、腹腔鏡手術 89例、taTME 1例、経肛門 1例、ロボット手術 189例）

　直腸がん 122例
（開腹術 2例、腹腔鏡下手術 21例、taTME 1 例、経肛門 1 例、ロボット手術 97例）

　結腸がん 161例
（開腹術 1例、腹腔鏡下手術 68例、ロボット手術 92例）

悪性リンパ腫 4例

GIST 3例

小腸・十二指腸がん 4例

再発がん 11例

人工肛門造設・閉鎖術 86例

痔核/痔瘻根治切除 22例

イレウス・ヘルニア 30例

炎症性腸疾患 7例

直腸脱 6例

他科手術支援 22例

その他 59例
論文: Insurance Co-Payment Status and Advanced-Stage Presentation of Colorectal Cancer in a Universal Healthcare System: A Surgical Cohort Study From Japan.
Kitagawa Y, Miki H, Yamamoto T, Watanabe J, Fukunaga Y.

World J Surg. 2026 Jul12. doi: 10.1002/wjs.70500. Epub ahead of print. PMID: 42437369.

Standardizing Upper Abdominal Fascial Terminology: A Transdisciplinary Expert Consensus From the Japanese Society for Endoscopic Surgery.
Watanabe J, Shinohara H, Obama K, Kinoshita T, Nagakawa Y, Nakata K, Kondo T, Miki J, Egi H, Sakai Y, Kitagawa Y.

Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70348. doi: 10.1111/ases.70348. PMID: 42427071; PMCID: PMC13351518.

Comparison of the short-term outcomes of robotic colorectal surgery between the hinotori™ surgical robot system and da Vinci Xi surgical system: a retrospective propensity score matching analysis and inverse probability of treatment weighting.
Hagiwara C, Uehara H, Yamada N, Igarashi Y, Fujita Y, Kobayashi T, Mori Y, Miki H, Watanabe J.

Surg Today. 2026 Jul 6. doi: 10.1007/s00595-026-03382-1. Epub ahead of print. PMID: 42406101.

Circulating Tumor DNA Status and Adjuvant Chemotherapy in Resected Colorectal Liver Metastases.
Kataoka K, Ito K, Nakamura Y, Watanabe J, Akazawa N, Nagata J, Yokota M, Kato K, Kotaka M, Hashimoto T, Yamazaki K, Kagawa Y, Mishima S, Ando K, Miyo M, Yukami H, Fungtammasan A, Sharma S, Ortiz JB, Rabinowitz M, Lentz RW, Jurdi A, Liu MC, Aleshin A, Kotani D, Bando H, Taniguchi H, Takemasa I, Kato T, Yoshino T, Oki E; CIRCULATE-Japan Group.

JAMA Oncol. 2026 Jul 3:1-10. doi: 10.1001/jamaoncol.2026.2191. Epub ahead of print. PMID: 42397676; PMCID: PMC13332432.

Post-adjuvant chemotherapy in ctDNA-positive patients with resected colorectal cancer: a randomized phase 3 trial.
Bando H, Watanabe J, Takahashi Y, Kotaka M, Matsuhashi N, Oki E, Komatsu Y, Shiozawa M, Hirata K, Miyamoto Y, Takahashi M, Yamazaki K, Manaka D, Kanazawa A, Liang YH, Yeh KH, Watsuji Y, Yamamoto Y, Fukui M, Sharma S, Aushev VN, Jurdi A, Rabinowitz M, Liu MC, Aleshin A, Takemasa I, Kotani D, Sato A, Misumi T, Nakamura Y, Shi Q, Taniguchi H, Yoshino T, Kato T.

Nat Med. 2026 Jul;32(7):2473-2480. doi: 10.1038/s41591-026-04428-0. Epub 2026 Jun 8. PMID: 42260101; PMCID: PMC13375530.

ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery. Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.
Sasaki S, Kitaguchi D, Ito M, Tanaka K, Yamaguchi T, Watanabe J, Hamamoto H,
Nishimura A, Fujita F, Inada R, Takahashi H, Miguchi M, Kayano H, Naitoh T,
Takemasa I.

Surg Endosc. 2026 Jun;40(6):4636-4645. doi: 10.1007/s00464-026-12783-9. Epub 2026 Apr 27. PMID: 42257961.

Long-term impact of diverting ileostomy after stoma closure on the renal function and risk factors for chronic kidney disease following colorectal tumor surgery.
Ota E, Watanabe J, Suwa H, Suwa Y, Nakagawa K, Ozawa M, Endo I.

Surg Today. 2026 Jun 6. doi: 10.1007/s00595-026-03357-2. Epub ahead of print. PMID: 42249907.

A modified Delphi consensus on fusion (laparoscopic and robotic) approaches to colorectal surgery in Asia-Pacific.
Watanabe J, Kagawa Y, Nonaka T, Kim H, Cheewatanakornkul S, Chen PC, Chen WT, deSouza A, Hamabe A, Kagawa H, Lee YS, Ng SS, Stevenson ARL, Teo NZ, Uemura M, Wong KY, Ngu JC.

J Gastroenterol. 2026 May 16. doi: 10.1007/s00535-026-02445-x. Epub ahead of print. PMID: 42143159.

Preoperative ctDNA and tumor volume predict colorectal cancer recurrence after metastasis resection.
Oyoshi H, Bando H, Yamashita R, Kageyama SI, Nakamura Y, Horasawa S, Nakamura M, Fujisawa T, Tomizawa K, Motegi A, Hojo H, Hirata H, Yukami H, Mishima S, Kotani D, Miyo M, Ando K, Watanabe J, Akazawa N, Kataoka K, Taniguchi H, Oki E, Takemasa I, Kato T, Mori M, Jurdi A, Liu MC, Misumi T, Zenda S, Yoshino T.

NPJ Precis Oncol. 2026 Apr 30;10(1):259. doi: 10.1038/s41698-026-01450-w. PMID: 42062528; PMCID: PMC13338026.

Hybrid robot-assisted surgery versus conventional fully robotic surgery for colon cancer: study protocol for a multicenter, parallel-group, single-blind randomized controlled superiority trial.
Watanabe J, Suwa Y, Mazaki J, Yokota M, Tsukamoto S, Kagawa Y, Uemura M, Hirano Y, Nonaka T.

BMC Surg. 2026 Apr 22;26(1):393. doi: 10.1186/s12893-026-03749-8. PMID: 42021265; PMCID:PMC13251096.

A Novel Laparoscopic Injection Needle for Abdominal Wall Nerve Block in Reduced Port Surgery.
Nagata J, Watanabe J, Nagata A, Sannomiya H, Nitta K, Koga A, Akiyama Y, Yamauchi M, Mori Y, Sato N, Tamura T, Shibao K, Hirata K.

Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70287. doi: 10.1111/ases.70287. PMID: 41958229; PMCID: PMC13066774.

A single-team, perineal-first approach for low rectal cancer: A novel modification of total mesorectal excision: A video vignette.
Miki H, Yamamoto T, Kitagawa Y, Watanabe J, Fukunaga Y.

Colorectal Dis. 2026 Apr;28(4):e70429. doi: 10.1111/codi.70429. PMID: 41891385.

Indocyanine green fluorescence angiography for anastomotic perfusion assessment in colorectal surgery: a systematic review with meta-analysis, meta-regression, and trial sequential analyses.
Ryan ÉJ, Ryan OK, Corrigan N, Ainsworth G, Hilling DE, Vahrmeijer AL, Kössi J, Watanabe J, Jayne D, Cahill RA.

Lancet Gastroenterol Hepatol. 2026 May;11(5):367-379. doi: 10.1016/S2468-1253(25)00373-5. Epub 2026 Mar 20. PMID: 41871586.

Urinary Function After Laparoscopic Surgery in Very Low Rectal Cancer.
Fukunaga Y, Tsukada Y, Akiyoshi T, Yamaguchi T, Watanabe J, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; ULTIMATE Trial Group in the Japan Society of Laparoscopic Colorectal Surgery.

Dis Colon Rectum. 2026 Jun 1;69(6):1741-1748. doi: 10.1097/DCR.0000000000004221. Epub 2026 Mar 23. PMID: 41870086.

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery.
Shinohara H, Kurahashi Y, Watanabe J, Nagakawa Y, Nakamura T, Nakao E, Hojo Y, Kohno S, Murakami M, Ishida Y.

Ann Gastroenterol Surg. 2025 Nov 4;10(2):372-385. doi: 10.1002/ags3.70117. PMID: 41799573; PMCID: PMC12962052.

Intracorporeal Anastomosis for Robotic-assisted Right Hemicolectomy Using an Umbilical Assistant Port.
Kitagawa Y, Miki H, Yamamoto T, Uehara H, I S, Yamada N, Igarashi Y, Kobayashi T, Mori Y, Watanabe J, Fukunaga Y.

J Anus Rectum Colon. 2026 Jan 25;10(1):184-188. doi: 10.23922/jarc.2025-044. PMID: 41623608; PMCID: PMC12854285.

Atypical Intestinal Metastases from Invasive Lobular Carcinoma of the Breast: Two Surgical Cases Mimicking Primary Gastrointestinal Tumors.
Kitagawa Y, Miki H, Yamamoto T, Sakai Y, Watanabe J, Fukunaga Y.

Surg Case Rep. 2025;11(1):25-0554. doi: 10.70352/scrj.cr.25-0554. Epub 2025 Dec 26. PMID:41536970; PMCID: PMC12796324.

Transanal drainage tube placement in patients with temporary ileostomy after laparoscopic rectal resection for rectal cancer.
Hoshino N, Hida K, Tsukada Y, Obama K, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group.

Updates Surg. 2026 Jun;78(3):993-999. doi: 10.1007/s13304-025-02503-8. Epub 2026 Jan 8. PMID: 41507457.

Protein-Losing Enteropathy Caused by Ascending Colon Cancer without Polyposis: A Rare Case Diagnosed by Scintigraphy.
Miki H, Yamamoto T, Kitagawa Y, Watanabe J, Fukunaga Y.

Surg Case Rep. 2025;11(1):25-0601. doi: 10.70352/scrj.cr.25-0601. Epub 2025 Dec 27. PMID: 41497708; PMCID: PMC12766160.

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer.
Kagawa Y, Watanabe J, Ando K, Kitchens C, Bercz A, Smith JJ.

Ann Gastroenterol Surg. 2025 Aug 24;10(1):145-153. doi: 10.1002/ags3.70083. PMID: 41488839; PMCID: PMC12757145.

The SPECTACLE Study: A Multicenter, Prospective, Single-Arm Trial Evaluating Quantitative Blood Flow Assessment Using SPY-QP Software in Minimally Invasive Rectal Cancer Surgery.
Hamabe A, Uemura M, Suwa Y, Nishizawa Y, Kagawa Y, Kimura K, Kondo A, Kato T, Katsuno G, Nitta T, Takano Y, Nagayoshi K, Miyanaga S, Matsuda T, Kawamura J, Watanabe J.

Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70209. doi: 10.1111/ases.70209. PMID: 41435911; PMCID: PMC12727126.

Patient-Reported Outcomes and Surgical Results of Hand-Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4-5 cm From the Anal Verge: A Subanalysis of the Ultimate Study.
Numata M, Watanabe J, Tsukada Y, Suwa Y, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery.

Ann Gastroenterol Surg. 2025 Jul 9;9(6):1215-1224. doi: 10.1002/ags3.70063. PMID: 41199980; PMCID: PMC12586937.

Surgical Procedure of Lateral Lymph Node Dissection for Advanced Lower Rectal Cancer.
Uemura M, Watanabe J, Shiomi A, Akiyoshi T, Chang GJ, Kanemitsu Y, Takemasa I, Sakai Y, Watanabe M, Endo I.

Ann Gastroenterol Surg. 2025 May 13;9(6):1112-1118. doi: 10.1002/ags3.70039. PMID: 41199967; PMCID: PMC12586956.

Quality of life after laparoscopic surgery for very low rectal cancer: A sub-analysis of the ultimate trial.
Hamamoto H, Tanaka K, Tsukada Y, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery.

Colorectal Dis. 2025 Oct;27(10):e70255. doi: 10.1111/codi.70255. PMID: 41054197; PMCID: PMC12501488.

Presence of Adipophilin-Positive Cancer-Associated Fibroblasts Is an Independent Poor Prognostic Indicator and Is Correlated with Immature-Type Desmoplastic Reaction in Patients with Colorectal Cancer.
Kobayashi T, Ishida M, Uehara H, I S, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Hirose Y, Watanabe J.

Cancers (Basel). 2025 Sep 15;17(18):3006. doi: 10.3390/cancers17183006. PMID: 41008850; PMCID: PMC12468228.

Molecular Residual Disease and Recurrence in Rectal Cancer Patients Undergoing Upfront Surgery: A Prospective Cohort Study.
Ando K, Hamabe A, Nakamura Y, Watanabe J, Hirata K, Kataoka K, Miyo M, Kato K, Akazawa N, Kagawa Y, Yokota M, Yamazaki K, Mishima S, Yukami H, Kotani D, Bando H, Laliotis G, Sharma S, Palsuledesai CC, Rabinowitz M, Jurdi A, Liu MC, Aleshin A, Taniguchi H, Takemasa I, Kato T, Yoshino T, Oki E.

Ann Surg. 2026 Jan 1;283(1):13-21. doi: 10.1097/SLA.0000000000006948. Epub 2025 Sep 26. PMID: 41002143; PMCID: PMC12695342.

A multicenter randomized controlled trial evaluating the effect of the use of an anti-adhesion barrier for diverting ileostomy on the multidimensional workload in minimally invasive surgery for rectal cancer (YCOG 2005: The ADOBARRIER study).
Ota E, Watanabe J, Suwa Y, Numata M, Suwa H, Ohya H, Nakagawa K, Ozawa M, Endo I.

Ann Gastroenterol Surg. 2025 Mar 6;9(5):971-979. doi: 10.1002/ags3.70009. Erratum in: Ann Gastroenterol Surg. 2025 Oct 02;10(1):287. doi: 10.1002/ags3.70102. PMID: 40922908; PMCID: PMC12414596.

Quantitative blood perfusion assessment by the SPY-QP software program for minimally invasive rectal cancer surgery.
Hagiwara C, Watanabe J, Suwa Y, Shoichiro I, Yamada N, Igarashi Y, Kobayashi T, Mori Y.

Surg Endosc. 2025 Nov;39(11):7505-7513. doi: 10.1007/s00464-025-12178-2. Epub 2025 Sep 5. PMID: 40913178.

Impact of the learning curve on the outcomes of robotic surgery in obese patients with rectal cancer.
Izukawa S, Numata M, Fukuda T, Harada T, Atsumi Y, Kazama K, Sawazaki S, Suzuki S, Godai T, Higuchi A, Tamagawa H, Suwa Y, Watanabe J, Sato T, Saito A.

Surg Today. 2026 Jan;56(1):36-46. doi: 10.1007/s00595-025-03113-y. Epub 2025 Sep 2. PMID: 40892105.

A multicenter trialevaluating the short-term outcomes of intracorporeal versus extracorporeal anastomosis in laparoscopic colectomy for overweight and obese patients withcolon cancer: a secondary analysis of the ICAN study.
Ota E, Watanabe J, Suwa H, Tanaka K, Yamaguchi T, Hamamoto H, Nishimura A, Fujita F, Ozawa H, Kobayashi K, Okada T, Todate Y, Naitoh T.

Surg Today. 2026 Feb;56(2):123-132. doi: 10.1007/s00595-025-03117-8. Epub 2025 Aug 21. PMID: 40841446.

Short-term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi-institutional cohort study in Japan (ICAN study).
Yamaguchi T, Tanaka K, Watanabe J, Hamamoto H, Nishimura A, Fujita F, Suwa H, Ito M, Kawai K, Hiro J, Yamamoto S, Nambara S, Ota M, Ito Y, Okuda J, Inomata M, Watanabe M, Naitoh T; ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery.

Ann Gastroenterol Surg. 2025 Jan 21;9(4):739-749. doi: 10.1002/ags3.12915. PMID: 40607305; PMCID: PMC12211091.

Clinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases.
Fujimoto K, Koyama F, Kobayashi H, Kotake K, Kawasaki M, Kanemitsu Y, Kinugasa Y, Ueno H, Maeda K, Suto T, Itabashi M, Funahashi K, Ozawa H, Noura S, Ishida H, Ohue M, Kiyomatsu T, Ishihara S, Koda K, Baba H, Kawada K, Hashiguchi Y, Goi T, Toiyama Y, Tomita N, Sunami E, Fujita F, Watanabe J, Hakamada K, Nakayama G, Sugihara K, Ajioka Y.

Ann Gastroenterol Surg. 2025 Jan 24;9(4):750-760. doi: 10.1002/ags3.12918. PMID: 40607290; PMCID: PMC12211111.

Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub-analysis of the ultimate trial.
Shimomura M, Yoshimitsu M, Tsukada Y, Ohdan H, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group.

Ann Gastroenterol Surg. 2025 Jan 7;9(4):719-729. doi: 10.1002/ags3.12904. PMID: 40607283; PMCID: PMC12211094.

A Randomized Open-Label, Noninferiority, Phase 3, Multicenter, Controlled Trial to Compare Laparoscopic Surgery With Open Surgery for Symptomatic, Noncurable Stage IV Colorectal Cancer (JCOG1107).
Akagi T, Inomata M, Kanzaka R, Katayama H, Fukuda H, Shiomi A, Ito M, Watanabe J, Murata K, Hirano Y, Shimomura M, Tsukamoto S, Hamaguchi T, Kitano S, Kanemitsu Y.

Ann Surg Open. 2025 Jun 2;6(2):e580. doi: 10.1097/AS9.0000000000000580. PMID: 40557341; PMCID: PMC12185070.

Fusion surgery in robotic-assisted sigmoid and rectosigmoid colectomy: A value-optimized stapling technique: A video vignette.
Kobayashi T, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Watanabe J.

Colorectal Dis. 2025 Jun;27(6):e70135. doi: 10.1111/codi.70135. PMID: 40462372.

A multicentre prospective study of anal function after laparoscopic ultra-low rectal cancer surgery using a mixed-effects model.
Takahashi M, Sakamoto K, Tsukada Y, Kawano S, Watanabe J, Fukunaga Y, Hirano Y, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group.

Colorectal Dis. 2025 May;27(5):e70129. doi: 10.1111/codi.70129. PMID: 40415353; PMCID: PMC12104611.

Longitudinal follow-up of sexual function after surgery for ultra-low rectal cancers located within 5 cm of the anal verge: A multicentre collaborative study.
Ishiyama Y, Hirano Y, Tsukada Y, Watanabe J, Fukunaga Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery.

Colorectal Dis. 2025 Apr;27(4):e70092. doi: 10.1111/codi.70092. PMID: 40251144; PMCID: PMC12008079.

Relationship of Desmoplastic Reaction and Tumour Budding in Primary and Lung Metastatic Lesions of Colorectal Cancer and Their Prognostic Significance.
Kobayashi T, Ishida M, Matsui H, Uehara H, I S, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Taniguchi Y, Saito T, Hino H, Hirose Y, Murakawa T, Watanabe J.

Cancers (Basel). 2025 Feb 8;17(4):583. doi: 10.3390/cancers17040583. PMID: 40002175; PMCID: PMC11852406.

Impact of Low Ligation on Bowel Perfusion and Anastomotic Leakage in Minimally Invasive Rectal Cancer Surgery: A Post Hoc Analysis of a Randomized Controlled Trial.
Kimura K, Watanabe J, Suwa Y, Kotake M, Noura S, Suwa H, Tei M, Takano Y, Munakata K, Matoba S, Yamagishi S, Yasui M, Kato T, Ozawa M, Shiozawa M, Ishii Y, Yabuno T, Nitta T, Saito S, Nagata N, Ichikawa D, Hasegawa S, Katsuno G, Takahashi H, Kawai K, Furuhata T, Tonooka T, Kanazawa A, Kuriu Y, Sakamoto K, Kinjo T, Otsuka H, Uemura M, Watanabe T, Ueda K, Ikeda M, Takemasa I, On thebehalf of EssentiAL Trial Group.

Dis Colon Rectum. 2025 May 1;68(5):544-552. doi: 10.1097/DCR.0000000000003669. Epub 2025 Feb 7. PMID: 39918199.

Factors Affecting the Prognosis after Primary Tumor Resection for Patients with Metastatic Colorectal Cancer with Synchronous Peritoneal Metastasis: A Multi-center, Prospective, Observational Study.
Kagami S, Funahashi K, Kobayashi H, Kotake K, Kawasaki M, Kinugasa Y, Ueno H, Maeda K, Suto T, Itabashi M, Ozawa H, Koyama F, Noura S, Ishida H, Ohue M, Kiyomatsu T, Ishihara S, Koda K, Baba H, Kawada K, Hashiguchi Y, Goi T, Toiyama Y, Tomita N, Sunami E, Fujita F, Watanabe J, Hakamada K, Nakayama G, Sugihara K, Ajioka Y.

J Anus Rectum Colon. 2025 Jan 25;9(1):134-144. doi: 10.23922/jarc.2024-056. PMID: 39882220; PMCID: PMC11772787.

Risk factors for anastomotic leakage in rectal cancer surgery reflecting current practices.
Harada T, Numata M, Atsumi Y, Fukuda T, Izukawa S, Suwa Y, Watanabe J, Sato T, Saito A.

Surg Today. 2025 Aug;55(8):1043-1051. doi: 10.1007/s00595-024-02988-7. Epub 2025 Jan 11. PMID: 39797981.

Antitraction sutures and indocyanine green fluorescence imaging to prevent anastomotic leakage in left-sided colorectal surgery-A video vignette.
Kobayashi T, Miki H, Hiroki U, Shoichiro I, Yamada N, Watanabe J.

Colorectal Dis. 2025 Jan;27(1):e17293. doi: 10.1111/codi.17293. PMID: 39763231.

A Tumor-Naïve ctDNA Assay Detects Minimal Residual Disease in Resected Stage II or III Colorectal Cancer and Predicts Recurrence: Subset Analysis from the GALAXY Study in CIRCULATE-Japan.
Nakamura Y, Kaneva K, Lo C, Neems D, Freaney JE, Boulos H, Hyun SW, Islam F, Yamada-Hanff J, Driessen TM, Sonnenschein A, DeSantis DF, Kotani D, Watanabe J, Kotaka M, Mishima S, Bando H, Yamazaki K, Taniguchi H, Takemasa I, Kato T, Sangli C, Tell R, Blidner R, Yoshino T, Sasser K, Oki E, Nimeiri H.

Clin Cancer Res. 2025 Jan 17;31(2):328-338. doi: 10.1158/1078-0432.CCR-24-2396. PMID: 39513962; PMCID: PMC11739780.

外来新患者数	371名
外来延患者数	9,281名
入院新患者数	810名
入院延患者数	10,420名

大腸
総手術数	537例
初発大腸がん	283例（開腹術 3例、腹腔鏡手術 89例、taTME 1例、経肛門 1例、ロボット手術 189例）
直腸がん	122例（開腹術 2例、腹腔鏡下手術 21例、taTME 1 例、経肛門 1 例、ロボット手術 97例）
結腸がん	161例（開腹術 1例、腹腔鏡下手術 68例、ロボット手術 92例）
悪性リンパ腫	4例
GIST	3例
小腸・十二指腸がん	4例
再発がん	11例
人工肛門造設・閉鎖術	86例
痔核/痔瘻根治切除	22例
イレウス・ヘルニア	30例
炎症性腸疾患	7例
直腸脱	6例
他科手術支援	22例
その他	59例

Insurance Co-Payment Status and Advanced-Stage Presentation of Colorectal Cancer in a Universal Healthcare System: A Surgical Cohort Study From Japan.	Kitagawa Y, Miki H, Yamamoto T, Watanabe J, Fukunaga Y. World J Surg. 2026 Jul12. doi: 10.1002/wjs.70500. Epub ahead of print. PMID: 42437369.
Standardizing Upper Abdominal Fascial Terminology: A Transdisciplinary Expert Consensus From the Japanese Society for Endoscopic Surgery.	Watanabe J, Shinohara H, Obama K, Kinoshita T, Nagakawa Y, Nakata K, Kondo T, Miki J, Egi H, Sakai Y, Kitagawa Y. Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70348. doi: 10.1111/ases.70348. PMID: 42427071; PMCID: PMC13351518.
Comparison of the short-term outcomes of robotic colorectal surgery between the hinotori™ surgical robot system and da Vinci Xi surgical system: a retrospective propensity score matching analysis and inverse probability of treatment weighting.	Hagiwara C, Uehara H, Yamada N, Igarashi Y, Fujita Y, Kobayashi T, Mori Y, Miki H, Watanabe J. Surg Today. 2026 Jul 6. doi: 10.1007/s00595-026-03382-1. Epub ahead of print. PMID: 42406101.
Circulating Tumor DNA Status and Adjuvant Chemotherapy in Resected Colorectal Liver Metastases.	Kataoka K, Ito K, Nakamura Y, Watanabe J, Akazawa N, Nagata J, Yokota M, Kato K, Kotaka M, Hashimoto T, Yamazaki K, Kagawa Y, Mishima S, Ando K, Miyo M, Yukami H, Fungtammasan A, Sharma S, Ortiz JB, Rabinowitz M, Lentz RW, Jurdi A, Liu MC, Aleshin A, Kotani D, Bando H, Taniguchi H, Takemasa I, Kato T, Yoshino T, Oki E; CIRCULATE-Japan Group. JAMA Oncol. 2026 Jul 3:1-10. doi: 10.1001/jamaoncol.2026.2191. Epub ahead of print. PMID: 42397676; PMCID: PMC13332432.
Post-adjuvant chemotherapy in ctDNA-positive patients with resected colorectal cancer: a randomized phase 3 trial.	Bando H, Watanabe J, Takahashi Y, Kotaka M, Matsuhashi N, Oki E, Komatsu Y, Shiozawa M, Hirata K, Miyamoto Y, Takahashi M, Yamazaki K, Manaka D, Kanazawa A, Liang YH, Yeh KH, Watsuji Y, Yamamoto Y, Fukui M, Sharma S, Aushev VN, Jurdi A, Rabinowitz M, Liu MC, Aleshin A, Takemasa I, Kotani D, Sato A, Misumi T, Nakamura Y, Shi Q, Taniguchi H, Yoshino T, Kato T. Nat Med. 2026 Jul;32(7):2473-2480. doi: 10.1038/s41591-026-04428-0. Epub 2026 Jun 8. PMID: 42260101; PMCID: PMC13375530.
ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery. Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.	Sasaki S, Kitaguchi D, Ito M, Tanaka K, Yamaguchi T, Watanabe J, Hamamoto H, Nishimura A, Fujita F, Inada R, Takahashi H, Miguchi M, Kayano H, Naitoh T, Takemasa I. Surg Endosc. 2026 Jun;40(6):4636-4645. doi: 10.1007/s00464-026-12783-9. Epub 2026 Apr 27. PMID: 42257961.
Long-term impact of diverting ileostomy after stoma closure on the renal function and risk factors for chronic kidney disease following colorectal tumor surgery.	Ota E, Watanabe J, Suwa H, Suwa Y, Nakagawa K, Ozawa M, Endo I. Surg Today. 2026 Jun 6. doi: 10.1007/s00595-026-03357-2. Epub ahead of print. PMID: 42249907.
A modified Delphi consensus on fusion (laparoscopic and robotic) approaches to colorectal surgery in Asia-Pacific.	Watanabe J, Kagawa Y, Nonaka T, Kim H, Cheewatanakornkul S, Chen PC, Chen WT, deSouza A, Hamabe A, Kagawa H, Lee YS, Ng SS, Stevenson ARL, Teo NZ, Uemura M, Wong KY, Ngu JC. J Gastroenterol. 2026 May 16. doi: 10.1007/s00535-026-02445-x. Epub ahead of print. PMID: 42143159.
Preoperative ctDNA and tumor volume predict colorectal cancer recurrence after metastasis resection.	Oyoshi H, Bando H, Yamashita R, Kageyama SI, Nakamura Y, Horasawa S, Nakamura M, Fujisawa T, Tomizawa K, Motegi A, Hojo H, Hirata H, Yukami H, Mishima S, Kotani D, Miyo M, Ando K, Watanabe J, Akazawa N, Kataoka K, Taniguchi H, Oki E, Takemasa I, Kato T, Mori M, Jurdi A, Liu MC, Misumi T, Zenda S, Yoshino T. NPJ Precis Oncol. 2026 Apr 30;10(1):259. doi: 10.1038/s41698-026-01450-w. PMID: 42062528; PMCID: PMC13338026.
Hybrid robot-assisted surgery versus conventional fully robotic surgery for colon cancer: study protocol for a multicenter, parallel-group, single-blind randomized controlled superiority trial.	Watanabe J, Suwa Y, Mazaki J, Yokota M, Tsukamoto S, Kagawa Y, Uemura M, Hirano Y, Nonaka T. BMC Surg. 2026 Apr 22;26(1):393. doi: 10.1186/s12893-026-03749-8. PMID: 42021265; PMCID:PMC13251096.
A Novel Laparoscopic Injection Needle for Abdominal Wall Nerve Block in Reduced Port Surgery.	Nagata J, Watanabe J, Nagata A, Sannomiya H, Nitta K, Koga A, Akiyama Y, Yamauchi M, Mori Y, Sato N, Tamura T, Shibao K, Hirata K. Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70287. doi: 10.1111/ases.70287. PMID: 41958229; PMCID: PMC13066774.
A single-team, perineal-first approach for low rectal cancer: A novel modification of total mesorectal excision: A video vignette.	Miki H, Yamamoto T, Kitagawa Y, Watanabe J, Fukunaga Y. Colorectal Dis. 2026 Apr;28(4):e70429. doi: 10.1111/codi.70429. PMID: 41891385.
Indocyanine green fluorescence angiography for anastomotic perfusion assessment in colorectal surgery: a systematic review with meta-analysis, meta-regression, and trial sequential analyses.	Ryan ÉJ, Ryan OK, Corrigan N, Ainsworth G, Hilling DE, Vahrmeijer AL, Kössi J, Watanabe J, Jayne D, Cahill RA. Lancet Gastroenterol Hepatol. 2026 May;11(5):367-379. doi: 10.1016/S2468-1253(25)00373-5. Epub 2026 Mar 20. PMID: 41871586.
Urinary Function After Laparoscopic Surgery in Very Low Rectal Cancer.	Fukunaga Y, Tsukada Y, Akiyoshi T, Yamaguchi T, Watanabe J, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; ULTIMATE Trial Group in the Japan Society of Laparoscopic Colorectal Surgery. Dis Colon Rectum. 2026 Jun 1;69(6):1741-1748. doi: 10.1097/DCR.0000000000004221. Epub 2026 Mar 23. PMID: 41870086.
Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery.	Shinohara H, Kurahashi Y, Watanabe J, Nagakawa Y, Nakamura T, Nakao E, Hojo Y, Kohno S, Murakami M, Ishida Y. Ann Gastroenterol Surg. 2025 Nov 4;10(2):372-385. doi: 10.1002/ags3.70117. PMID: 41799573; PMCID: PMC12962052.
Intracorporeal Anastomosis for Robotic-assisted Right Hemicolectomy Using an Umbilical Assistant Port.	Kitagawa Y, Miki H, Yamamoto T, Uehara H, I S, Yamada N, Igarashi Y, Kobayashi T, Mori Y, Watanabe J, Fukunaga Y. J Anus Rectum Colon. 2026 Jan 25;10(1):184-188. doi: 10.23922/jarc.2025-044. PMID: 41623608; PMCID: PMC12854285.
Atypical Intestinal Metastases from Invasive Lobular Carcinoma of the Breast: Two Surgical Cases Mimicking Primary Gastrointestinal Tumors.	Kitagawa Y, Miki H, Yamamoto T, Sakai Y, Watanabe J, Fukunaga Y. Surg Case Rep. 2025;11(1):25-0554. doi: 10.70352/scrj.cr.25-0554. Epub 2025 Dec 26. PMID:41536970; PMCID: PMC12796324.
Transanal drainage tube placement in patients with temporary ileostomy after laparoscopic rectal resection for rectal cancer.	Hoshino N, Hida K, Tsukada Y, Obama K, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group. Updates Surg. 2026 Jun;78(3):993-999. doi: 10.1007/s13304-025-02503-8. Epub 2026 Jan 8. PMID: 41507457.
Protein-Losing Enteropathy Caused by Ascending Colon Cancer without Polyposis: A Rare Case Diagnosed by Scintigraphy.	Miki H, Yamamoto T, Kitagawa Y, Watanabe J, Fukunaga Y. Surg Case Rep. 2025;11(1):25-0601. doi: 10.70352/scrj.cr.25-0601. Epub 2025 Dec 27. PMID: 41497708; PMCID: PMC12766160.
Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer.	Kagawa Y, Watanabe J, Ando K, Kitchens C, Bercz A, Smith JJ. Ann Gastroenterol Surg. 2025 Aug 24;10(1):145-153. doi: 10.1002/ags3.70083. PMID: 41488839; PMCID: PMC12757145.
The SPECTACLE Study: A Multicenter, Prospective, Single-Arm Trial Evaluating Quantitative Blood Flow Assessment Using SPY-QP Software in Minimally Invasive Rectal Cancer Surgery.	Hamabe A, Uemura M, Suwa Y, Nishizawa Y, Kagawa Y, Kimura K, Kondo A, Kato T, Katsuno G, Nitta T, Takano Y, Nagayoshi K, Miyanaga S, Matsuda T, Kawamura J, Watanabe J. Asian J Endosc Surg. 2026 Jan-Dec;19(1):e70209. doi: 10.1111/ases.70209. PMID: 41435911; PMCID: PMC12727126.
Patient-Reported Outcomes and Surgical Results of Hand-Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4-5 cm From the Anal Verge: A Subanalysis of the Ultimate Study.	Numata M, Watanabe J, Tsukada Y, Suwa Y, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery. Ann Gastroenterol Surg. 2025 Jul 9;9(6):1215-1224. doi: 10.1002/ags3.70063. PMID: 41199980; PMCID: PMC12586937.
Surgical Procedure of Lateral Lymph Node Dissection for Advanced Lower Rectal Cancer.	Uemura M, Watanabe J, Shiomi A, Akiyoshi T, Chang GJ, Kanemitsu Y, Takemasa I, Sakai Y, Watanabe M, Endo I. Ann Gastroenterol Surg. 2025 May 13;9(6):1112-1118. doi: 10.1002/ags3.70039. PMID: 41199967; PMCID: PMC12586956.
Quality of life after laparoscopic surgery for very low rectal cancer: A sub-analysis of the ultimate trial.	Hamamoto H, Tanaka K, Tsukada Y, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery. Colorectal Dis. 2025 Oct;27(10):e70255. doi: 10.1111/codi.70255. PMID: 41054197; PMCID: PMC12501488.
Presence of Adipophilin-Positive Cancer-Associated Fibroblasts Is an Independent Poor Prognostic Indicator and Is Correlated with Immature-Type Desmoplastic Reaction in Patients with Colorectal Cancer.	Kobayashi T, Ishida M, Uehara H, I S, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Hirose Y, Watanabe J. Cancers (Basel). 2025 Sep 15;17(18):3006. doi: 10.3390/cancers17183006. PMID: 41008850; PMCID: PMC12468228.
Molecular Residual Disease and Recurrence in Rectal Cancer Patients Undergoing Upfront Surgery: A Prospective Cohort Study.	Ando K, Hamabe A, Nakamura Y, Watanabe J, Hirata K, Kataoka K, Miyo M, Kato K, Akazawa N, Kagawa Y, Yokota M, Yamazaki K, Mishima S, Yukami H, Kotani D, Bando H, Laliotis G, Sharma S, Palsuledesai CC, Rabinowitz M, Jurdi A, Liu MC, Aleshin A, Taniguchi H, Takemasa I, Kato T, Yoshino T, Oki E. Ann Surg. 2026 Jan 1;283(1):13-21. doi: 10.1097/SLA.0000000000006948. Epub 2025 Sep 26. PMID: 41002143; PMCID: PMC12695342.
A multicenter randomized controlled trial evaluating the effect of the use of an anti-adhesion barrier for diverting ileostomy on the multidimensional workload in minimally invasive surgery for rectal cancer (YCOG 2005: The ADOBARRIER study).	Ota E, Watanabe J, Suwa Y, Numata M, Suwa H, Ohya H, Nakagawa K, Ozawa M, Endo I. Ann Gastroenterol Surg. 2025 Mar 6;9(5):971-979. doi: 10.1002/ags3.70009. Erratum in: Ann Gastroenterol Surg. 2025 Oct 02;10(1):287. doi: 10.1002/ags3.70102. PMID: 40922908; PMCID: PMC12414596.
Quantitative blood perfusion assessment by the SPY-QP software program for minimally invasive rectal cancer surgery.	Hagiwara C, Watanabe J, Suwa Y, Shoichiro I, Yamada N, Igarashi Y, Kobayashi T, Mori Y. Surg Endosc. 2025 Nov;39(11):7505-7513. doi: 10.1007/s00464-025-12178-2. Epub 2025 Sep 5. PMID: 40913178.
Impact of the learning curve on the outcomes of robotic surgery in obese patients with rectal cancer.	Izukawa S, Numata M, Fukuda T, Harada T, Atsumi Y, Kazama K, Sawazaki S, Suzuki S, Godai T, Higuchi A, Tamagawa H, Suwa Y, Watanabe J, Sato T, Saito A. Surg Today. 2026 Jan;56(1):36-46. doi: 10.1007/s00595-025-03113-y. Epub 2025 Sep 2. PMID: 40892105.
A multicenter trialevaluating the short-term outcomes of intracorporeal versus extracorporeal anastomosis in laparoscopic colectomy for overweight and obese patients withcolon cancer: a secondary analysis of the ICAN study.	Ota E, Watanabe J, Suwa H, Tanaka K, Yamaguchi T, Hamamoto H, Nishimura A, Fujita F, Ozawa H, Kobayashi K, Okada T, Todate Y, Naitoh T. Surg Today. 2026 Feb;56(2):123-132. doi: 10.1007/s00595-025-03117-8. Epub 2025 Aug 21. PMID: 40841446.
Short-term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi-institutional cohort study in Japan (ICAN study).	Yamaguchi T, Tanaka K, Watanabe J, Hamamoto H, Nishimura A, Fujita F, Suwa H, Ito M, Kawai K, Hiro J, Yamamoto S, Nambara S, Ota M, Ito Y, Okuda J, Inomata M, Watanabe M, Naitoh T; ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery. Ann Gastroenterol Surg. 2025 Jan 21;9(4):739-749. doi: 10.1002/ags3.12915. PMID: 40607305; PMCID: PMC12211091.
Clinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases.	Fujimoto K, Koyama F, Kobayashi H, Kotake K, Kawasaki M, Kanemitsu Y, Kinugasa Y, Ueno H, Maeda K, Suto T, Itabashi M, Funahashi K, Ozawa H, Noura S, Ishida H, Ohue M, Kiyomatsu T, Ishihara S, Koda K, Baba H, Kawada K, Hashiguchi Y, Goi T, Toiyama Y, Tomita N, Sunami E, Fujita F, Watanabe J, Hakamada K, Nakayama G, Sugihara K, Ajioka Y. Ann Gastroenterol Surg. 2025 Jan 24;9(4):750-760. doi: 10.1002/ags3.12918. PMID: 40607290; PMCID: PMC12211111.
Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub-analysis of the ultimate trial.	Shimomura M, Yoshimitsu M, Tsukada Y, Ohdan H, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group. Ann Gastroenterol Surg. 2025 Jan 7;9(4):719-729. doi: 10.1002/ags3.12904. PMID: 40607283; PMCID: PMC12211094.
A Randomized Open-Label, Noninferiority, Phase 3, Multicenter, Controlled Trial to Compare Laparoscopic Surgery With Open Surgery for Symptomatic, Noncurable Stage IV Colorectal Cancer (JCOG1107).	Akagi T, Inomata M, Kanzaka R, Katayama H, Fukuda H, Shiomi A, Ito M, Watanabe J, Murata K, Hirano Y, Shimomura M, Tsukamoto S, Hamaguchi T, Kitano S, Kanemitsu Y. Ann Surg Open. 2025 Jun 2;6(2):e580. doi: 10.1097/AS9.0000000000000580. PMID: 40557341; PMCID: PMC12185070.
Fusion surgery in robotic-assisted sigmoid and rectosigmoid colectomy: A value-optimized stapling technique: A video vignette.	Kobayashi T, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Watanabe J. Colorectal Dis. 2025 Jun;27(6):e70135. doi: 10.1111/codi.70135. PMID: 40462372.
A multicentre prospective study of anal function after laparoscopic ultra-low rectal cancer surgery using a mixed-effects model.	Takahashi M, Sakamoto K, Tsukada Y, Kawano S, Watanabe J, Fukunaga Y, Hirano Y, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group. Colorectal Dis. 2025 May;27(5):e70129. doi: 10.1111/codi.70129. PMID: 40415353; PMCID: PMC12104611.
Longitudinal follow-up of sexual function after surgery for ultra-low rectal cancers located within 5 cm of the anal verge: A multicentre collaborative study.	Ishiyama Y, Hirano Y, Tsukada Y, Watanabe J, Fukunaga Y, Sakamoto K, Hamamoto H, Yoshimitsu M, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Naitoh T, Watanabe M, Suzuki M, Misumi T, Ito M; Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery. Colorectal Dis. 2025 Apr;27(4):e70092. doi: 10.1111/codi.70092. PMID: 40251144; PMCID: PMC12008079.
Relationship of Desmoplastic Reaction and Tumour Budding in Primary and Lung Metastatic Lesions of Colorectal Cancer and Their Prognostic Significance.	Kobayashi T, Ishida M, Matsui H, Uehara H, I S, Yamada N, Igarashi Y, Hagiwara C, Mori Y, Taniguchi Y, Saito T, Hino H, Hirose Y, Murakawa T, Watanabe J. Cancers (Basel). 2025 Feb 8;17(4):583. doi: 10.3390/cancers17040583. PMID: 40002175; PMCID: PMC11852406.
Impact of Low Ligation on Bowel Perfusion and Anastomotic Leakage in Minimally Invasive Rectal Cancer Surgery: A Post Hoc Analysis of a Randomized Controlled Trial.	Kimura K, Watanabe J, Suwa Y, Kotake M, Noura S, Suwa H, Tei M, Takano Y, Munakata K, Matoba S, Yamagishi S, Yasui M, Kato T, Ozawa M, Shiozawa M, Ishii Y, Yabuno T, Nitta T, Saito S, Nagata N, Ichikawa D, Hasegawa S, Katsuno G, Takahashi H, Kawai K, Furuhata T, Tonooka T, Kanazawa A, Kuriu Y, Sakamoto K, Kinjo T, Otsuka H, Uemura M, Watanabe T, Ueda K, Ikeda M, Takemasa I, On thebehalf of EssentiAL Trial Group. Dis Colon Rectum. 2025 May 1;68(5):544-552. doi: 10.1097/DCR.0000000000003669. Epub 2025 Feb 7. PMID: 39918199.
Factors Affecting the Prognosis after Primary Tumor Resection for Patients with Metastatic Colorectal Cancer with Synchronous Peritoneal Metastasis: A Multi-center, Prospective, Observational Study.	Kagami S, Funahashi K, Kobayashi H, Kotake K, Kawasaki M, Kinugasa Y, Ueno H, Maeda K, Suto T, Itabashi M, Ozawa H, Koyama F, Noura S, Ishida H, Ohue M, Kiyomatsu T, Ishihara S, Koda K, Baba H, Kawada K, Hashiguchi Y, Goi T, Toiyama Y, Tomita N, Sunami E, Fujita F, Watanabe J, Hakamada K, Nakayama G, Sugihara K, Ajioka Y. J Anus Rectum Colon. 2025 Jan 25;9(1):134-144. doi: 10.23922/jarc.2024-056. PMID: 39882220; PMCID: PMC11772787.
Risk factors for anastomotic leakage in rectal cancer surgery reflecting current practices.	Harada T, Numata M, Atsumi Y, Fukuda T, Izukawa S, Suwa Y, Watanabe J, Sato T, Saito A. Surg Today. 2025 Aug;55(8):1043-1051. doi: 10.1007/s00595-024-02988-7. Epub 2025 Jan 11. PMID: 39797981.
Antitraction sutures and indocyanine green fluorescence imaging to prevent anastomotic leakage in left-sided colorectal surgery-A video vignette.	Kobayashi T, Miki H, Hiroki U, Shoichiro I, Yamada N, Watanabe J. Colorectal Dis. 2025 Jan;27(1):e17293. doi: 10.1111/codi.17293. PMID: 39763231.
A Tumor-Naïve ctDNA Assay Detects Minimal Residual Disease in Resected Stage II or III Colorectal Cancer and Predicts Recurrence: Subset Analysis from the GALAXY Study in CIRCULATE-Japan.	Nakamura Y, Kaneva K, Lo C, Neems D, Freaney JE, Boulos H, Hyun SW, Islam F, Yamada-Hanff J, Driessen TM, Sonnenschein A, DeSantis DF, Kotani D, Watanabe J, Kotaka M, Mishima S, Bando H, Yamazaki K, Taniguchi H, Takemasa I, Kato T, Sangli C, Tell R, Blidner R, Yoshino T, Sasser K, Oki E, Nimeiri H. Clin Cancer Res. 2025 Jan 17;31(2):328-338. doi: 10.1158/1078-0432.CCR-24-2396. PMID: 39513962; PMCID: PMC11739780.